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An existential crisis for Alzheimer's research?

What a new study comparing living and dead brain tissue means for our understanding of the disease

In this episode, we discuss a study published in PLOS One that compared living brain tissue to post-mortem brain tissue and found dramatic molecular differences between the two.

The findings raise serious questions about decades of Alzheimer’s research built on post-mortem analysis and may help explain why pharmaceutical treatments for the disease have been so disappointing

Study: A Study of RNA Splicing and Protein Expression in the Living Human Brain

Josh and Tommy

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