Is a ketogenic diet safe for me?
Exploring the interaction between a ketogenic diet, dysbiosis, and genetics.
In this episode, Dr. Tommy Wood addresses Jean's question regarding the ketogenic diet's role in cognitive enhancement, discussing its potential to increase gut-derived endotoxins and the impact of genetic markers like APOE4 and PPAR.
Ketogenic Diet and Cognitive Function: Do ketogenic diets and exogenous ketones have a role for improving cognitive impairment and processing speed?
Bacterial Endotoxins and Dysbiosis: Does a ketogenic diet increase the secretion of bacterial endotoxins from the gut, and should dysbiosis be addressed before starting such a diet?
Genetic Factors in Diet Suitability: How do genetics, specifically the APOE4 gene and polymorphisms in the PPAR gene, affect the suitability and effectiveness of a ketogenic diet for an individual?
Effects of Ketones and Cognitive Function: What have various studies and trials indicated about the use of MCT oils and the impact of ketone levels on cognitive function, especially in relation to the APOE4 genotype?
Dietary Choices and Metabolic Health: How do broader dietary choices impact metabolic health, inflammation, and cognitive function, and how does this vary with genetic predispositions?
Future Research and Trials: What can be expected from future clinical trials regarding the role of ketogenic diets in cognitive health and disease prevention?